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新会员聚光灯:XYLYX生物

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beplay华为下载再生医学一般是一个非常雄心勃勃的事业。通过重新承载最小一组条件来制作功能体部件,仍然存在主要障碍,以了解成熟,功能性人体组织所需的全套条件。为肺或肝等器官制作功能单位的策略是非常复杂的:复杂的材料,复杂的生物反应器系统等。仍然有很长的路要走,Xylyx看到使用细胞外基质(ECM)生物材料作为绝对重要的部分这一切都。

XYLYX BIO的驾驶使命和激情是为人类生活和健康创造和提供有效的科学解决方案。“beplay华为下载再生医学通过使人们能够实现更长,更健康的生活来巨大潜力,”Xylyx生物,补充说,“我们很荣幸能够支持再生医学的努力,以实现有意义的差异在人类生活的质量和持续时间。“

XYLYX BIO.www.xylyxbio.com.)2016年纺出了哥伦比亚大学的干细胞和组织工程的着名实验室,以将基质生物改造进行组织再生和完全细胞健康。“正如环境对植物和动物的宏观规模的事项一样,这对细胞的微观规模至关重要,”John O'Noiil,Xylyx的创始人和首席科学官员解释说。认识到本地细胞微环境的重要性,Xylyx生物是利用组织特异性细胞外基质,身体的天然细胞环境的力量,用于药物发现和组织再生。

“虽然人体能够进行再生的能力持有潜力,但它也涉及由于再生中涉及的复杂性,”NYE表示,“为了帮助解决这一挑战,Xylyx开发了一种可以作为基础的平台技术to instruct and guide regeneration by leveraging the body’s natural mechanisms that have evolved over time based on fundamental interactions between cells and the ECM in which those cells naturally reside.”

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通过从天然器官和组织中采购细胞外基质,Xylyx产生组织特异性底物,其包括特异性和组织和器官型特异性和独特的ECM组分的机械性能和复杂比。根据需要和预期用途,XYLYX产品来自人或动物来源。该公司从医疗等级组织供应商获得天然猪组织,并捐赠人器官被拒绝用于移植或从同意供体中的组织。XYLYX产品以各种浓度的形式提供,包括组织特异性水凝胶,表面涂层和无细胞支架。

“对于成功的组织工程,关键重要的是,组织工程三合会的所有组分都被定制为特定的组织应用 - 即生物材料,用作结构基质,促进组织形成的细胞源和生长因子direct cell growth and differentiation,” O’Neill explained, “When developing bio-inspired replacement tissues, the tissue-specific three-dimensional (3D) biomaterial scaffolds and other products that Xylyx manufactures play a critical role in the development of new tissue morphogenesis via interaction with human cells.”

“穆克·雷丁的战略联盟主任Mara Neal被引入Armi,”NYE评论道。“拥有超过30年的实验室诊断空间经验,有超过12年的经验,帮助学术创新者将其创新商业化,Mara密切地了解将新技术与市场带来的挑战和障碍。在公司甚至形成之前,她是在哥伦比亚大学支持俄罗斯大学的Xylyx技术的一部分,通过她的专业知识,深度知识和专业网络提供了一家重要的支持和鼓励来源。当Mara告诉我们Armi成员可以提供的机会时,我们很激动。“

“就再生医学的未来而言,我们希望在下一代生物活性疗法中beplay华为下载看到爆炸。The conventional approach has been one drug, one molecule, or one compound delivered in its molecular form with one or two target effects and associated potential off-target effects,” explained O’Neill, adding, “A deeper understanding of the comprehensive nature of tissues and cells and their interaction with the cellular microenvironment – that is, the extracellular matrix – will likely lead to a paradigm shift to therapeutics and treatments that are more comprehensive in scope. In addition, the emergence of ECM as a bioactive class of biomaterials that can be deployed on its own or as a carrier for other therapies is likely to be an exciting new area of exploration.”

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“Through ARMI, Xylyx will be ideally positioned to work closely with other members towards integrating extracellular matrix as a bioactive class of biomaterials,” said John O’Neill, adding,” We hope to establish close collaborations, support meaningful work and share and provide our resources towards the goal of contributing to the field of regenerative medicine. It’s going to take collaborative teamwork and an “army” (ARMI!) of like-minded people working together towards the same goal,” he concluded.

Xylyx为ARMI社区带来了帮助支持有用的设备,协议和ECM生物材料的广泛图书馆的能力,可用于生物医学研究,评估和作为组织工程医疗产品的组成部分的能力。Xylyx是合作和伙伴关系开放的,并认为这是公司成长和成功以及该领域的关键部分,“我们欢迎与ARMI社区成员合作的机会!”纽约说。